Cellular Therapies
Stem Cell Therapies
They are the mother cells of embryological origin. In other words, they are the starting cells. They are the cell groups from which all cells originate and then differentiate. They can differentiate into 3 germ layers (endoderm, mesoderm, ectoderm) at the same time. In our body, these cells are present in bone marrow, adipose tissue, connective tissue and blood cells. They are in reserve in their untransformed initial state. In case of any tissue destruction or damage, they take part in repairing the target tissue and organ.
Stem cells have been used in diagnosis and treatment for many years. It has been observed that cells obtained from adult tissues (bone marrow, adipose tissue, connective tissues, etc.) can transform into stem cells with embryological characteristics as a result of reconstruction. Again, they can transform into different tissue cells when stimulated by different signaling. What distinguishes this is the way they divide. In symmetric division, it reproduces with the characteristics of the cell from which it originates, while in asymmetric division, it evolves into the desired cell shape by giving different stimuli.
This ability to divide (proliferate) and differentiate for a long time accelerates healing. It has also opened the doors of long life to humanity by extending the telomere structure due to its long-term division feature.
Areas of Use
Although it is increasing day by day, there are studies with all diseases in regenerative medicine. Repairing damaged areas; allows regeneration and healing.
It is used in the repair of damage after chemotherapy and radio therapy applied in cancer diseases as well as diseases such as thalassemia major, sickle cell anemia, multiple myeloma, acute leukemias, crohn’s disease, acute-chronic renal failure, type 2 diabetes.
Dermatologically, it can be used for allapesia, acne scars, wound-burn healing, spot treatment and regeneration of skin structure.
Neurologically, it is important to use it in Alzheimer’s patients, spinal cord injuries, cell destruction after myocardial infarction, liver regeneration, trachea and cornea reconstructions.
Stem Cells Can Be Obtained by Different Methods
SVF. The material taken from the stromal vascular frozen adipose tissue is subjected to enzymatic and mechanical processes and the stem cells in it are separated. This complex stem cell containing suspension is called SVF. It is administered parantenally (intravenously).
Mesenchymal stem cell fraction is obtained from connective tissue. Material from bone marrow and adipose tissue can transform into bone, cartilage, nerve, liver and pancreatic cells.
In order to increase their number, they are grown in special laboratories in cultures lasting for weeks. It is a very costly procedure that requires very high technology and time.
Efforts to save this high cost and time have led us to new sources. One of the most effective of these is EXOSOMEs.
CD34 and CGELL stem cell therapies are also highly effective and time-saving methods that can be applied in clinical settings.